since they retard protein synthesis and accelerate its ..
Dutch National Institute of Public Health and Environmental Protection panel
Glucocorticoid effects on the immune system - UpToDate
Suggested determinations are: calcium, phosphorus, chloride, sodium, potassium, fasting glucose, serum alanine aminotransferase, serum aspartate aminotransferase, ornithine decarboxylase, gamma-glutamyl transpeptidase, urea nitrogen, albumin, blood creatinine, total bilirubin, and total serum protein.
Kramer CM, Johnson KW, Dooley RK, & Holsapple MP (1987) 2,3,7,8- Tetrachlorodibenzo- p-dioxin (TCDD) enhances antibody production and protein kinase activity in murine B cells.
(And, by extension, what's in our bodies)
IL-1 has (together with IL-6 and tumour necrosis factor) multiple effects in the systemic acute-phase response and in local acute and chronic inflammation: it stimulates T (helper) cells to synthesize IL-2 and IL-2 receptors, interferon gamma, and other lymphokines, B cells (proliferation and differentiation), neutrophils, and natural killer cells; stimulates monocytes and macrophages to produce IL-1, IL-6, and tumour necrosis factor; acts in the acute-phase response by inducing synthesis of acute-phase proteins in liver and reducing cytochrome P450 synthesis; induces natriuresis in kidney, insulin production in pancreas ß cells, muscular proteolysis ('easy' energy generation) in muscle cells, slow-wave sleep in cerebral cortex; raises the temperature set-point (fever) in hypothalamus; stimulates haematopoiesis and prostaglandin synthesis by various cell types (fibroblasts, macrophages, endothelium); inhibits gastric motility in vitro ; induces collagenase production by synovial cells and osteoclasts, and antiviral state; inhibits gastric smooth muscle in vitro ; is cytostatic for tumour cells and activates endothelium Interleukin 2.
Family of heterodimeric molecules sharing a ß chain (ß1, ß2, ß3, about 750 amino acids long), each with a different alpha chain (about 1100 amino acids long), with a major function in cell adhesion and migration.
Global strategy for asthma management and prevention…
Synthesized by fibroblasts and bone-marrow stromal cells; resembles IL-6 in function: stimulates haematopoietic cell growth and differentiation (myeloid, erythroid, megakaryocyte lineage); enhances T-cell-dependent antibody response; and suppresses adipocyte differentiation and lipoprotein lipase production Interleukin 12.
Formerly called neutrophil-activating protein; synthesized by monocytes and various tissue cells in response to inflammatory stimuli; performs chemotaxis of neutrophilic granulocytes and subsequent granule exocytosis and respiratory burst; induces increased expression of adhesion molecules CD11b/CD18 (complement C3 receptor CR3) and promotes vascular leakage.
Eosinophilic Inflammation in Asthma — NEJM
Trimovate - - (eMC) - Medicines
Vos, National Institute of Public Health and Environmental Protection, Bilthoven, Netherlands (Chairman) Dr K.L.
Decadron - FDA prescribing information, side effects …
Dexamethasone Alters Arachidonate Release from Human Epithelial Cells by Induction of p11 Protein Synthesis and ..
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09/04/2001 · This may result in increased or decreased protein synthesis and ..
Proceedings of the American Thoracic Society - ATS …
Group of molecules including immunoglobulins, T-cell receptors, MHC molecules, and others, like the lymphocyte function-related antigens LFA-2 (CD2) and LFA-3 (CD58), the intercellular adhesion molecules ICAM-1 (CD54) and ICAM-2, the vascular cell adhesion molecule VCAM-1, the neural cell adhesion molecule NCAM (CD56), and the CD4 and CD8 molecules, which have a similar tertiary basic domain-like structure, in which each domain is about 110 amino acids long and stabilized by a disulfide bridge.
Allergic and nonallergic rhinitis affect approximately 30% of the U.S
For immunoglobulin and T-cell receptor, the process whereby the germline chromosomal genomic structure of variable (diversity), joining, and constant segments recombine to form a specific V-(D-)J-C combination, enabling transcription into mRNA and translation into protein.
American Journal of Respiratory and Critical Care Medicine
Molecules of the immunoglobulin gene superfamily have a tertiary domain-like structure: each domain is about 110 amino acids long and arranged in a sandwich of two sheets of anti-parallel ß strands.
CS are frequently used, systemically or by inhalation
Formerly called interferon ß2; synthesized by T cells, monocytes, endothelial cells, fibroblasts, and smooth muscle cells, among others, during inflammatory reactions; stimulates T and B cells to proliferate and differentiate; has properties similar to IL-1 and acts synergistically with it in the acute-phase response (fever, synthesis of acute-phase proteins); synergizes with IL-3 in promoting haematopoietic progenitor cell proliferation; inhibits production of IL-1 and tumour necrosis factor by monocytes Interleukin 7.
This protein binding likely decreases ..
to single- or double-stranded DNA or histone proteins); frequently observed in patients with rheumatoid arthritis, scleroderma, Sjögren's syndrome, systemic lupus erythematosus, and mixed connective tissue disease.
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