The morpholine rings carry A, C, G or T bases positioned suitably for Watson-Crick base pairing.
Only Morpholino oligos provide all of these.
R.; Duddu, R.; Yang, K.; Damavarapu, R.; Gelber, N.; Surapaneni, R.; Gilardi, R., Preparation of cage molecule based polyazido core units for dendrimer synthesis.
K.; Chen, Y.-J.; Lin, C.-c., Site-specific protein modification through CuI-catalyzed 1,2,3-triazole formation and its implementation in protein microarray fabrication.
You'll find papers related to probe applications .
R.; Lober, S.; Hubner, H.; Gmeiner, P., Click chemistry on solid phase: parallel synthesis of -benzyltriazole carboxamides as super-potent G-protein coupled receptor ligands.
R., Activity-Based Protein Profiling Reagents for Protein Arginine Deaminase 4 (PAD4): Synthesis and in vitro Evaluation of a Fluorescently Labeled Probe.
You can order Morpholinos with these groups attached: ().
a.; Liu, Y.; Qin, J., An Attempt To Modify Nonlinear Optical Effects of Polyurethanes by Adjusting the Structure of the Chromophore Moieties at the Molecular Level Using "Click" Chemistry.
L.; Struthers, H.; Brans, L.; Anguelov, T.; Schweinsberg, C.; Maes, V.; Tourwe, D.; Schibli, R., "Click to Chelate": Synthesis and Installation of Metal Chelates into Biomolecules in a Single Step.
Therefore we recommend ordering 25-mers, our longest available oligo.
This amine can be acylated under suitable conditions.
Morpholino - Wikipedia
1,000 nmol and 6,000 nmol sizes (delivered quantity) are available.
FAQ | Gene Tools, LLC
Vivo-Morpholinos take a day or two more.
Vivo-Morpholinos are also effective and easy to use in cultures.
Assessing the Suitability of 1,2,3-Triazole Linkers for Covalent Immobilization of Chiral Ligands: Application to Enantioselective Phenylation of Aldehydes.
For syntheses greater than 10000 nmol please contact .
B., Synthesis of azide-alkyne fragments for click' chemical applications; formation of oligomers from orthogonally protected trialkylsilyl-propargyl azides and propargyl alcohols.
All Vivo-Morpholinos are sterilized.
Telechelic Poly(-isopropylacrylamides) via Nitroxide-Mediated Controlled Polymerization and "Click" Chemistry: Livingness and "Grafting-from" Methodology.
For a typical 20g mouse injected at 12.5 mg/kg I.V.
Surface-modified Nanoparticles via Thermal and Cu(I)-Mediated "Click" Chemistry: Generation of luminescent CdSe Nanoparticles with Polar Ligands Guiding Supramolecular Recognition.
the dose is approximately 25 nmole per injection.
Synthesis of Enantiomerically Pure α-[4-(1-Substituted)-1,2,3-triazol-4-yl]-benzylacetamides via Microwave-Assisted Click Chemistry: Towards New Potential Antimicrobial Agents.
Local injections should be performed with reduced doses.
M.; Jang, H.; Kirshenbaum, K., Clickity-click: highly functionalized peptoid oligomers generated by sequential conjugation reactions on solid-phase support.
For short term experiments (3-day) suggests two days of i.v.
Synthesis and Supramolecular Structures of N3P3(N(Me)N=CHC6F5)6, -N3P3(C12H8O2)(N(Me)N=CHC6F5)4, and -N3P3(C12H8O2)2(N(Me)N=CHC6F5)2.
injections at 12.5 mg/kg followed by analysis on day 3.
Synthesis of Azide/Alkyne-Terminal Polymers and Application for Surface Functionalisation through a [2 + 3] Huisgen Cycloaddition Process, "Click Chemistry".
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